A 14-year study of 5,423 adults linked cardiovascular disease to faster cognitive decline, with patterns differing by long-term depressive symptoms.

A Nature Medicine study found menopause-stage protein changes associated with cognitive outcomes and modestly higher later Alzheimer’s risk.

A two-week cinaciguat study restored features of aging liver cells in rats and halved blood amyloid beta. Human effects are unknown.

A Tiny Buddha contributor describes why she stopped drinking, including blackouts, anxiety, family concerns and a changing view of social drinking.

A Norwegian analysis of 2,252 patients found no significant 12-month disability benefit from adding spinal fusion to decompression surgery.

A study using data from nearly 2.8 million people identified 127 Alzheimer’s risk loci and found that common-variant heritability estimates depend on the method used.

A Swedish cohort study found higher type 1 diabetes risk among children whose parents had autoimmune disease, with the strongest associations for parental type 1.